Recent Advancements in Synthesis of Phenanthridines via 2-Isocyanobiphenyls

Ashutosh Dey; Vikash Kumar; Rana Chatterjee; Ananya Behera; Rohit Kumar Maurya; Amarender Goud Burra; Shubham Kumar; Mahender Khatravath; Rambabu Dandella

doi:10.1002/ajoc.202300369

Recent Advancements in Synthesis of Phenanthridines via 2-Isocyanobiphenyls

Ashutosh Dey, Vikash Kumar, Rana Chatterjee, Ananya Behera, Rohit Kumar Maurya, Amarender Goud Burra, Shubham Kumar, Mahender Khatravath, Rambabu Dandella

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Phenanthridines are a privileged heterocyclic compound that exists in many natural products and has been known to exhibit a variety of pharmacological properties. In the last few decades, an incredible development has taken place to synthesise this scaffold. In this regard, 2-isocyanobiphenyl has become one of the most exploited substrates that allow the direct formation of phenanthridine derivatives under various novel and conventional methods. The present review provides an overview of synthetic approaches for the preparation of phenanthridine, and their derivatives form 2-isocyanobiphenyls′′.

Original language	English
Article number	e202300369
Journal	Asian Journal of Organic Chemistry
Volume	12
Issue number	11
DOIs	https://doi.org/10.1002/ajoc.202300369
State	Published - 1 Nov 2023
Externally published	Yes

Keywords

Isonitriles
Phenanthridines
Radical Cyclization
Trifluoromethylation
light induced cyclization

ASJC Scopus subject areas

Organic Chemistry

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10.1002/ajoc.202300369

Cite this

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title = "Recent Advancements in Synthesis of Phenanthridines via 2-Isocyanobiphenyls",

abstract = "Phenanthridines are a privileged heterocyclic compound that exists in many natural products and has been known to exhibit a variety of pharmacological properties. In the last few decades, an incredible development has taken place to synthesise this scaffold. In this regard, 2-isocyanobiphenyl has become one of the most exploited substrates that allow the direct formation of phenanthridine derivatives under various novel and conventional methods. The present review provides an overview of synthetic approaches for the preparation of phenanthridine, and their derivatives form 2-isocyanobiphenyls′′.",

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AU - Dey, Ashutosh

AU - Kumar, Vikash

AU - Chatterjee, Rana

AU - Behera, Ananya

AU - Maurya, Rohit Kumar

AU - Burra, Amarender Goud

AU - Kumar, Shubham

AU - Khatravath, Mahender

AU - Dandella, Rambabu

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AB - Phenanthridines are a privileged heterocyclic compound that exists in many natural products and has been known to exhibit a variety of pharmacological properties. In the last few decades, an incredible development has taken place to synthesise this scaffold. In this regard, 2-isocyanobiphenyl has become one of the most exploited substrates that allow the direct formation of phenanthridine derivatives under various novel and conventional methods. The present review provides an overview of synthetic approaches for the preparation of phenanthridine, and their derivatives form 2-isocyanobiphenyls′′.

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KW - Phenanthridines

KW - Radical Cyclization

KW - Trifluoromethylation

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Recent Advancements in Synthesis of Phenanthridines via 2-Isocyanobiphenyls

Abstract

Keywords

ASJC Scopus subject areas

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