Recent advances and future prospective of hybrid drug delivery systems

The development of nanotechnology bought a significant effect in the field of drug delivery and biomedicine. There are plethora of published studies mentioning the importance of nanocarriers in biomedical applications. Nanoparticles are studied extensively due to their unique properties to deliver drugs/genes to specific site, which prevents reaching these agents to undesired tissue or cell. Several inorganic and organic nanoparticles are used to encapsulate or attach drug molecules which improves their therapeutic value. However, the approach of development of hybrid nanocarriers can alter the release pattern from various nanocarriers such as nanogels, dendrimers, quantum dots, liposomes etc., providing next-generation therapeutic efficacy. Hybrid drug delivery system in many clinical trials have shown as an excellent performer in improving the therapeutic property of drug by increasing solubility and membrane permeability. This kind of delivery systems encapsulate drug in such a way that they can reach target site without affecting the normal cell or tissue. In this chapter, we are going to have the overview of different organicinorganic nanohybrids along with their recent development in the field of drug delivering and targeting. This chapter also provides information regarding the recent advancement in area of design, fabrication, and bioactivity of each nanohybrids along with their future prospective.