TY - JOUR
T1 - Recurrent Neisseria meningitidis Bacteremia
T2 - Association With Deficiency of the Eighth Component of Complement (C8) in a Sephardic Jewish Family
AU - Zimran, Ari
AU - Kuperman, Oded
AU - Shemesh, Ovadia
AU - Hershko, Chaim
PY - 1984/1/1
Y1 - 1984/1/1
N2 - A 24-year-old man had repeated episodes of meningococcal meningitis. Selective deficiency of the eighth component of complement (C8) was demonstrated in the patient, his twin brother, and in one of five siblings. As the parents were first cousins of normal phenotype, this pattern is suggestive of an autosomal recessive heredity. The present report brings the total number of patients given the diagnosis of C8 deficiency to 14, and calls attention to the existence of this condition in Jews of Sephardic (Mediterranean) origin.
AB - A 24-year-old man had repeated episodes of meningococcal meningitis. Selective deficiency of the eighth component of complement (C8) was demonstrated in the patient, his twin brother, and in one of five siblings. As the parents were first cousins of normal phenotype, this pattern is suggestive of an autosomal recessive heredity. The present report brings the total number of patients given the diagnosis of C8 deficiency to 14, and calls attention to the existence of this condition in Jews of Sephardic (Mediterranean) origin.
UR - https://www.scopus.com/pages/publications/0021278427
U2 - 10.1001/archinte.1984.00350190187031
DO - 10.1001/archinte.1984.00350190187031
M3 - Article
C2 - 6732408
AN - SCOPUS:0021278427
SN - 0003-9926
VL - 144
SP - 1481
EP - 1482
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 7
ER -
