@inproceedings{626e3a29b7ef45d18c71383128456e34,
title = "Reduced graphene oxide-modified microelectrode for antipsychotic clozapine detection in finger-pricked blood",
abstract = "Clozapine (CLZ) is the most effective antipsychotic medication for schizophrenia and the only one whose efficacy can be predicted by a blood test. However, it is underutilized due to adverse side effects and burdensome treatment monitoring scheme. Here, we present the development of an electrochemical microsystem based on a microelectrode modified with reduced graphene oxide to enable minimally invasive, real-time and in situ monitoring of CLZ levels in a finger-pricked volume sample of undiluted serum. The outcome of this work will facilitate the development of miniaturized and wearable analytical devices, and will enable personalized schizophrenia treatment management.",
keywords = "Clozapine, Microsystem, Reduced graphene oxide, Schizophrenia",
author = "Shukla, {Rajendra P.} and Remi Cazelles and Kelly, {Deanna L.} and Hadar Ben-Yoav",
note = "Funding Information: The authors thank the Brain and Behavior Research Foundation (Grant No. 26038) for funding the Project and IIse Katz Institute for Nanoscale Science and Technology at Ben‐Gurion University of the Negev, for their help in microelectrode microfabrication and material characterization. The authors also thank the Krietman School for Midway Negev fellowship and Marcus Postdoctoral Fellowships in Water Sciences Program. Publisher Copyright: {\textcopyright} 2019 CBMS-0001.; 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 ; Conference date: 27-10-2019 Through 31-10-2019",
year = "2019",
month = jan,
day = "1",
language = "English",
series = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
publisher = "Chemical and Biological Microsystems Society",
pages = "1324--1325",
booktitle = "23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019",
}