Regioselective monoalkylation of dimethyl alkylidenesuccinates: Simple approach to dialkyl-substituted maleic anhydrides including chaetomellic acid A

Umesh A. Kshirsagar; Narshinha P. Argade

doi:10.1055/s-0030-1260013

Regioselective monoalkylation of dimethyl alkylidenesuccinates: Simple approach to dialkyl-substituted maleic anhydrides including chaetomellic acid A

Umesh A. Kshirsagar
, Narshinha P. Argade

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Natural and nonnatural dialkylmaleic anhydrides were readily prepared from dimethyl alkylidenesuccinates by sodium hexamethyldisilazide-induced selective monoalkylation followed by base-catalyzed hydrolysis.

Original language	English
Pages (from-to)	1804-1808
Number of pages	5
Journal	Synthesis
Issue number	11
DOIs	https://doi.org/10.1055/s-0030-1260013
State	Published - 27 May 2011
Externally published	Yes

Keywords

alkylations
esters
furans
heterocycles
maleic anhydrides

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1055/s-0030-1260013

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title = "Regioselective monoalkylation of dimethyl alkylidenesuccinates: Simple approach to dialkyl-substituted maleic anhydrides including chaetomellic acid A",

abstract = "Natural and nonnatural dialkylmaleic anhydrides were readily prepared from dimethyl alkylidenesuccinates by sodium hexamethyldisilazide-induced selective monoalkylation followed by base-catalyzed hydrolysis.",

keywords = "alkylations, esters, furans, heterocycles, maleic anhydrides",

author = "Kshirsagar, \{Umesh A.\} and Argade, \{Narshinha P.\}",

year = "2011",

month = may,

day = "27",

doi = "10.1055/s-0030-1260013",

language = "English",

pages = "1804--1808",

journal = "Synthesis",

issn = "0039-7881",

publisher = "Georg Thieme Verlag",

number = "11",

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T1 - Regioselective monoalkylation of dimethyl alkylidenesuccinates

T2 - Simple approach to dialkyl-substituted maleic anhydrides including chaetomellic acid A

AU - Kshirsagar, Umesh A.

AU - Argade, Narshinha P.

PY - 2011/5/27

Y1 - 2011/5/27

N2 - Natural and nonnatural dialkylmaleic anhydrides were readily prepared from dimethyl alkylidenesuccinates by sodium hexamethyldisilazide-induced selective monoalkylation followed by base-catalyzed hydrolysis.

AB - Natural and nonnatural dialkylmaleic anhydrides were readily prepared from dimethyl alkylidenesuccinates by sodium hexamethyldisilazide-induced selective monoalkylation followed by base-catalyzed hydrolysis.

KW - alkylations

KW - esters

KW - furans

KW - heterocycles

KW - maleic anhydrides

UR - https://www.scopus.com/pages/publications/79956372411

U2 - 10.1055/s-0030-1260013

DO - 10.1055/s-0030-1260013

M3 - Article

AN - SCOPUS:79956372411

SN - 0039-7881

SP - 1804

EP - 1808

JO - Synthesis

JF - Synthesis

IS - 11

ER -

Regioselective monoalkylation of dimethyl alkylidenesuccinates: Simple approach to dialkyl-substituted maleic anhydrides including chaetomellic acid A

Abstract

Keywords

ASJC Scopus subject areas

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