Relationships between platelet and plasma monoamine oxidase, plasma dopamine-B-hydroxylase, and urinary 3-methoxy-4-hydroxy phenylglycol

Robert Belmaker, Helmut Beckmann, Frederick Goodwin, Dennis Murphy, William Pollin, Monte Buchsbaum, Richard Wyatt, Roland Ciaranello, Friedhelm Lamprecht

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

The activity of dopamine-B-hydroxylase in blood has recently been demonstrated to be under genetic control and to correlate closely with urinary catecholamine excretion. The results of the present study did not demonstrate any relationship between a major catecholamine metabolite in urine, 3-methoxy-4-hydroxy phenylglycol, and dopamine-B-hydroxylase activity in plasma, monoamine oxidase activity in platelets, or monoamine oxidase activity in plasma. Differences in the origin of urinary catecholamines and urinary 3-methoxy-4-hydroxy phenyglycol may be responsible for these divergent results.

Original languageEnglish
Pages (from-to)273-279
Number of pages7
JournalLife Sciences
Volume16
Issue number2
DOIs
StatePublished - 15 Jan 1975
Externally publishedYes

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