@inbook{190c76b8353544339a137762906eeb55,
title = "Reliable Patient-Specific Simulations of the Femur",
abstract = "Valuable simulations aimed at diagnosis and optimal treatment in clinical orthopedic practice should demonstrate that their results are verified, validated by experimental observations and obtained on a patient-specific level in a short time-scale. Such verified and validated simulations, based on CT-scans, were recently introduced using high-order finite element methods (p-FEMs), demonstrating an unprecedented prediction capability. We describe herein the methods used for creating p-FEM models of patient-specific femurs (including assignment of inhomogeneous material properties) and the large set of in-vitro experiments used to assess the validity of the simulation results. We thereafter extend the simulation capabilities for the analysis of bone fixations by metallic inserts, demonstrating again the high quality results. Such reliable patient-specific simulations are in an advanced stage to be used on a daily basis in clinical practice.",
keywords = "Gauss Point, Isotropic Material Property, Optical Marker, Orthotropic Model, Principal Strain Direction",
author = "Zohar Yosibash and Nir Trabelsi",
note = "Funding Information: We would like to thank Prof. Charles Milgrom from the Hadassah Hospital, Jerusalem, for femurs supply and his help with the CT-scans and experiments. Special thanks are extended to Mr. Alon Katz, a graduate student under the supervision of the first author, for his help with FE analyses and experiments. The authors gratefully acknowledge the generous support of the Technische Universit{\"a}t M{\"u}nchen–Institute for Advanced Study and International Graduate School of Science and Engineering, funded by the German Excellence Initiative, which made parts of this research possible. Funding Information: Acknowledgements We would like to thank Prof. Charles Milgrom from the Hadassah Hospital, Jerusalem, for femurs supply and his help with the CT-scans and experiments. Special thanks are extended to Mr. Alon Katz, a graduate student under the supervision of the first author, for his help with FE analyses and experiments. The authors gratefully acknowledge the generous support of the Technische Universit{\"a}t M{\"u}nchen–Institute for Advanced Study and International Graduate School of Science and Engineering, funded by the German Excellence Initiative, which made parts of this research possible. Publisher Copyright: {\textcopyright} 2011, Springer-Verlag Berlin Heidelberg.",
year = "2012",
month = jan,
day = "1",
doi = "10.1007/8415_2011_89",
language = "English",
series = "Studies in Mechanobiology, Tissue Engineering and Biomaterials",
publisher = "Springer",
pages = "3--26",
booktitle = "Studies in Mechanobiology, Tissue Engineering and Biomaterials",
address = "Germany",
}