Renal cell carcinoma in a child presented as bilateral femur neck fractures caused by severe vitamin D deficiency

Shraga Aviner, Dan Dabby, Daniel London, Meora Feinmesser, Shifra Ash, Ran Steinberg, Itzhak Jakim

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

An Ethiopian girl 14 years and 11 months of age presented with bilateral transcervical hip fractures. Workup revealed severe vitamins D and C deficiencies with secondary hyperparathyroidism. Imaging studies showed bilateral radiolucent metaphyseal bands with multiple lytic lesions in long bones. A mass in the right flank was found to be renal cell carcinoma (RCC). Currently, 9 months postsurgery and supplemental therapy, the patient is fully ambulatory and free of pain. This first report of asymptomatic RCC in severely vitamin D deficient child highlights the relation of RCC to vitamin D deficiency and emphasizes the importance of careful evaluation of these children.

Original languageEnglish
Pages (from-to)848-850
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume29
Issue number12
DOIs
StatePublished - 1 Dec 2007

Keywords

  • Brown tumor
  • Hip fracture
  • Renal cell carcinoma
  • Secondary hyperparathyroidism
  • Vitamin D deficiency

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