Renal cell carcinoma in a child presented as bilateral femur neck fractures caused by severe vitamin D deficiency

Shraga Aviner; Dan Dabby; Daniel London; Meora Feinmesser; Shifra Ash; Ran Steinberg; Itzhak Jakim

doi:10.1097/MPH.0b013e3181581587

Renal cell carcinoma in a child presented as bilateral femur neck fractures caused by severe vitamin D deficiency

Shraga Aviner, Dan Dabby, Daniel London, Meora Feinmesser, Shifra Ash, Ran Steinberg, Itzhak Jakim

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

An Ethiopian girl 14 years and 11 months of age presented with bilateral transcervical hip fractures. Workup revealed severe vitamins D and C deficiencies with secondary hyperparathyroidism. Imaging studies showed bilateral radiolucent metaphyseal bands with multiple lytic lesions in long bones. A mass in the right flank was found to be renal cell carcinoma (RCC). Currently, 9 months postsurgery and supplemental therapy, the patient is fully ambulatory and free of pain. This first report of asymptomatic RCC in severely vitamin D deficient child highlights the relation of RCC to vitamin D deficiency and emphasizes the importance of careful evaluation of these children.

Original language	English
Pages (from-to)	848-850
Number of pages	3
Journal	Journal of Pediatric Hematology/Oncology
Volume	29
Issue number	12
DOIs	https://doi.org/10.1097/MPH.0b013e3181581587
State	Published - 1 Dec 2007

Keywords

Brown tumor
Hip fracture
Renal cell carcinoma
Secondary hyperparathyroidism
Vitamin D deficiency

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/MPH.0b013e3181581587

Cite this

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title = "Renal cell carcinoma in a child presented as bilateral femur neck fractures caused by severe vitamin D deficiency",

abstract = "An Ethiopian girl 14 years and 11 months of age presented with bilateral transcervical hip fractures. Workup revealed severe vitamins D and C deficiencies with secondary hyperparathyroidism. Imaging studies showed bilateral radiolucent metaphyseal bands with multiple lytic lesions in long bones. A mass in the right flank was found to be renal cell carcinoma (RCC). Currently, 9 months postsurgery and supplemental therapy, the patient is fully ambulatory and free of pain. This first report of asymptomatic RCC in severely vitamin D deficient child highlights the relation of RCC to vitamin D deficiency and emphasizes the importance of careful evaluation of these children.",

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T1 - Renal cell carcinoma in a child presented as bilateral femur neck fractures caused by severe vitamin D deficiency

AU - Aviner, Shraga

AU - Dabby, Dan

AU - London, Daniel

AU - Feinmesser, Meora

AU - Ash, Shifra

AU - Steinberg, Ran

AU - Jakim, Itzhak

PY - 2007/12/1

Y1 - 2007/12/1

N2 - An Ethiopian girl 14 years and 11 months of age presented with bilateral transcervical hip fractures. Workup revealed severe vitamins D and C deficiencies with secondary hyperparathyroidism. Imaging studies showed bilateral radiolucent metaphyseal bands with multiple lytic lesions in long bones. A mass in the right flank was found to be renal cell carcinoma (RCC). Currently, 9 months postsurgery and supplemental therapy, the patient is fully ambulatory and free of pain. This first report of asymptomatic RCC in severely vitamin D deficient child highlights the relation of RCC to vitamin D deficiency and emphasizes the importance of careful evaluation of these children.

AB - An Ethiopian girl 14 years and 11 months of age presented with bilateral transcervical hip fractures. Workup revealed severe vitamins D and C deficiencies with secondary hyperparathyroidism. Imaging studies showed bilateral radiolucent metaphyseal bands with multiple lytic lesions in long bones. A mass in the right flank was found to be renal cell carcinoma (RCC). Currently, 9 months postsurgery and supplemental therapy, the patient is fully ambulatory and free of pain. This first report of asymptomatic RCC in severely vitamin D deficient child highlights the relation of RCC to vitamin D deficiency and emphasizes the importance of careful evaluation of these children.

KW - Brown tumor

KW - Hip fracture

KW - Renal cell carcinoma

KW - Secondary hyperparathyroidism

KW - Vitamin D deficiency

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AN - SCOPUS:37349090439

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Renal cell carcinoma in a child presented as bilateral femur neck fractures caused by severe vitamin D deficiency

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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