TY - JOUR
T1 - Renal clearance of urea, inulin, and p-aminohippurate in heat-acclimated rats
AU - Chayoth, R.
AU - Kleinman, D.
AU - Kaplanski, J.
AU - Sod Moriah, U. A.
PY - 1984/1/1
Y1 - 1984/1/1
N2 - Clearance values of urea, inulin, and p-aminohippurate (PAH) were measured in heat-acclimated (HA) rats exposed for 3 wk to 35°C, in control rats (C) exposed to 23°C, and in HA rats deacclimated (DA) for 3 wk. In HA rats, urea clearance was lower by 73%, inulin clearance by 61%, and PAH clearance by 56%, compared with C rats. The clearance values of these substances returned to the control values in DA rats. The data suggest that the low clearance values reflect both reduced renal blood flow and possible changes in the capacity of the glomeruli for filtration and the tubules for either reabsorption or secretion.
AB - Clearance values of urea, inulin, and p-aminohippurate (PAH) were measured in heat-acclimated (HA) rats exposed for 3 wk to 35°C, in control rats (C) exposed to 23°C, and in HA rats deacclimated (DA) for 3 wk. In HA rats, urea clearance was lower by 73%, inulin clearance by 61%, and PAH clearance by 56%, compared with C rats. The clearance values of these substances returned to the control values in DA rats. The data suggest that the low clearance values reflect both reduced renal blood flow and possible changes in the capacity of the glomeruli for filtration and the tubules for either reabsorption or secretion.
UR - http://www.scopus.com/inward/record.url?scp=0021208830&partnerID=8YFLogxK
U2 - 10.1152/jappl.1984.57.3.731
DO - 10.1152/jappl.1984.57.3.731
M3 - Article
AN - SCOPUS:0021208830
SN - 0161-7567
VL - 57
SP - 731
EP - 732
JO - Journal of Applied Physiology Respiratory Environmental and Exercise Physiology
JF - Journal of Applied Physiology Respiratory Environmental and Exercise Physiology
IS - 3
ER -