Renin and aldosterone levels and hypertension following envenomation in humans by the yellow scorpion Leiurus quinquestriatus

M. Gueron, R. Ilia, E. Shahak, S. Sofer

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28 Scopus citations

Abstract

Renin activity and aldosterone blood levels were measured in ten patients following scorpion envenomation by the scorpion Leiurus quinquestriatus. All patients were hypertensive on admission, with clinical signs of systemic intoxication. The blood renin and aldosterone levels were elevated in all ten patients. The observation of high blood pressure and elevated levels of renin suggests that in addition to increased circulating catecholamines following scorpion envenomation, sympathetically induced renin release may play an important role in the pathogenesis of hypertension. This observation re-emphasizes the importance of afterload reduction in the treatment of the cardiovascular manifestations of scorpion envenomation.

Original languageEnglish
Pages (from-to)765-767
Number of pages3
JournalToxicon
Volume30
Issue number7
DOIs
StatePublished - 1 Jan 1992
Externally publishedYes

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