Repair of pig dura in vivo using temperature controlled CO2 laser soldering

Boaz Forer, Tamar Vasilyev, Tamar Brosh, Noam Kariv, Ziv Gil, Dan M. Fliss, Abraham Katzir

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Background and Objectives: The purpose of this study was to demonstrate that laser soldering might be successfully used for closing holes or cuts in the dura layer, which encapsulates the brain. Study Design/Materials and Methods: A temperature controlled fiberoptic CO2 laser system and albumin solder were used for spot soldering of fascia patches to holes in the dura of farm pigs, in vitro and in vivo. Results: The mean burst pressure of the soldered patches in the in vitro experiments was 190 ± 88 mm Hg-significantly higher than typical maximum CSF pressure of 15 mm Hg. In the in vivo experiments the pigs showed no postoperative complications. Histopathological studies exhibited an accepted level of inflammatory reaction and showed no thermal damage to the underlying brain tissue. Conclusions: It has been clearly demonstrated that temperature controlled laser soldering is a very useful technique for the repair of the dura. It provides significant advantages over standard closure techniques: it is easy to apply, the bond is strong and watertight and the procedure is likely to be much faster than suturing. This research work will lead to clinical trials.

Original languageEnglish
Pages (from-to)286-292
Number of pages7
JournalLasers in Surgery and Medicine
Issue number4
StatePublished - 1 Oct 2005
Externally publishedYes


  • Albumin solder
  • Burst pressure
  • Dural closure
  • Fascia patch
  • Infrared fibers
  • Laser welding

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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