Replication NAND gate with light as input and output

Manickasundaram Samiappan, Zehavit Dadon, Gonen Ashkenasy

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Logic operations can highlight information transfer within complex molecular networks. We describe here the design of a peptide-based replication system that can be detected by following its fluorescence quenching. This process is used to negate the signal of light-activated replication, and thus to prepare the first replication NAND gate.

Original languageEnglish
Pages (from-to)710-712
Number of pages3
JournalChemical Communications
Issue number2
StatePublished - 14 Dec 2011


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