Residue-level determinants of angiopoietin-2 interactions with its receptor Tie2

Keyphrases

• Angiopoietin-2 100%
• Residue Level 100%
• Receptor Tyrosine Kinase 20%
• Yeast Surface Display 20%
• Inflammation 10%
• Deleterious Effects 10%
• Angiogenesis 10%
• Signaling System 10%
• Granulocyte Colony-stimulating Factor (G-CSF) 10%
• Tumorigenesis 10%
• Intermolecular Interactions 10%
• Oncogenesis 10%
• Receptor Binding 10%
• Large Set 10%
• Site-directed mutagenesis 10%
• Computational Analysis 10%
• Ligand Complexes 10%
• C-kit 10%
• Physics-based 10%
• Area Calculation 10%
• Interfacial Residues 10%
• 2-structure 10%
• Combined Methodology 10%
• Multiple mutations 10%
• Binding Determinants 10%

Biochemistry, Genetics and Molecular Biology

• Angiopoietin-2 100%
• Angiopoietin Receptor 100%
• Surface Property 20%
• Carcinogenesis 20%
• Receptor Tyrosine Kinase 20%
• Angiogenesis 10%
• Static Electricity 10%
• Surface Area 10%
• Site-Directed Mutagenesis 10%
• Receptor Binding 10%
• Macrophage Colony-Stimulating Factor 10%