Resistance to activated protein C: arterial thrombosis associated with autoimmune features.

O. Yossepowitch, T. Chajek-Shaul, A. Rubinow, Y. S. Haviv, R. Safadi

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A 27 year old woman presented with recurrent cerebrovascular strokes in the setting of an ill defined auto-immune disease responsive to corticosteroid therapy. Investigation for a hypercoagulable state revealed activated protein C resistance in the absence of protein C, protein S, or antithrombin III deficiency or anticardiolipin antibodies. Her parents and sibling did not demonstrate APC resistance. This case suggests that activated protein C resistance may be associated with arterial as well as venous thrombotic events and implies that resistance to activated protein C should also be considered in the evaluation of young adults with strokes.

Original languageEnglish
Pages (from-to)355-357
Number of pages3
JournalEuropean Journal of Medical Research
Volume2
Issue number8
StatePublished - 1 Jan 1997
Externally publishedYes

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