Respiratory viral and pneumococcal coinfection of the respiratory tract: Implications of pneumococcal vaccination

David Paul Moore, Ron Dagan, Shabir Ahmed Madhi

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The interactions between Streptococcus pneumoniae and other respiratory pathogens have been studied in vitro, in animal models and in humans - including epidemiologic and vaccine probe studies. Interactions of pneumococcus with respiratory viruses are common, and many mechanisms have been suggested to explain this phenomenon. The aim of this review is to explore pneumococcal interactions with respiratory viruses and consider the potential role that the pneumococcal polysaccharide-protein conjugate vaccine may play in modifying pneumococcal-respiratory viral interactions.

Original languageEnglish
Pages (from-to)451-465
Number of pages15
JournalExpert Review of Respiratory Medicine
Volume6
Issue number4
DOIs
StatePublished - 1 Jan 2012
Externally publishedYes

Keywords

  • coinfection
  • effectiveness
  • efficacy
  • pneumococcus
  • respiratory viruses
  • vaccination

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