Abstract
The ideal drug-delivery system should provide therapeutics in response to physiological requirements, having the capacity to 'sense' changes and alter the drug-release process accordingly. Such responsive controlled delivery systems are still at an experimental stage. This review focuses on two basic approaches: (1) externally regulated systems (utilizing triggers such as magnetism, ultrasound, temperature and electricity), and (2) self-regulated systems (utilizing pH-sensitive polymers, enzyme-substrate reactions, competitive binding, and antibody interactions).
Original language | English |
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Pages (from-to) | 127-131 |
Number of pages | 5 |
Journal | Trends in Biotechnology |
Volume | 10 |
Issue number | C |
DOIs | |
State | Published - 1 Jan 1992 |
ASJC Scopus subject areas
- Biotechnology
- Bioengineering