Abstract
This paper discusses the state of the art in a relatively new approach in the field of controlled drug delivery-responsive polymeric drug delivery systems. Such systems are capable of adjusting drug release rates in response to a physiological need. The fundamental principles of externally and self-regulated delivery systems are examined. Special attention is paid to specific clinical settings such as diabetes, presenting the advantages and disadvantages of different approaches.
| Original language | English |
|---|---|
| Pages (from-to) | 125-148 |
| Number of pages | 24 |
| Journal | Advanced Drug Delivery Reviews |
| Volume | 46 |
| Issue number | 1-3 |
| DOIs | |
| State | Published - 1 Mar 2001 |
Keywords
- Controlled drug delivery
- Controlled release
- Environmentally sensitive polymer
- Externally regulated drug delivery
- Insulin delivery
- Pulsatile drug delivery
- Self-regulated drug delivery
ASJC Scopus subject areas
- Pharmaceutical Science
