Rett syndrome and aging

Joav Merrick; Joav Merrick; Meir Lotan; Meir Lotan; Meir Lotan; Mohammed Morad; Mohammed Morad; Isack Kandle

doi:10.1515/IJDHD.2006.5.1.23

Rett syndrome and aging

Joav Merrick, Joav Merrick, Meir Lotan, Meir Lotan, Meir Lotan, Mohammed Morad, Mohammed Morad, Isack Kandle

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Rett syndrome (RS) is a neurological disease characterized by an arrest of brain development caused by an X chromosome mutation affecting mainly females. Rett syndrome is the first human disease found to be caused by defects in a protein involved in regulating gene expression through its interaction with methylated DNA. The disease has been traced to a defective gene called MECP2 on the X chromosome. This review of aging with RS revealed very few studies, but the published case stories showed that females with RS can live even to age 79 years, but larger studies are needed to bring more light into the natural and long-term consequences of this syndrome.

Original language	English
Pages (from-to)	23-26
Number of pages	4
Journal	International Journal on Disability and Human Development
Volume	5
Issue number	1
DOIs	https://doi.org/10.1515/IJDHD.2006.5.1.23
State	Published - 1 Jan 2006
Externally published	Yes

Keywords

Aging
Israel
Rett syndrome
long-term care

ASJC Scopus subject areas

Rehabilitation
Sensory Systems
Geriatrics and Gerontology
Psychiatry and Mental health
Advanced and Specialized Nursing
Speech and Hearing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1515/IJDHD.2006.5.1.23

Cite this

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JO - International Journal on Disability and Human Development

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ER -

Rett syndrome and aging

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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