Review: Inhibition of bacterial quorum sensing by plant extracts

Bacterial quorum sensing (QS) is a form of cell-to-cell communication which is vital to the pathogenicity of many bacteria, and therefore a promising target for the development of new treatments for microbial infections. While many medicinal plants possess antibacterial activity, only a few plants have been shown to target quorum sensing. In the face of increased microbial resistance to existing antibiotics coupled with the decline in novel antibiotic development, QS inhibitors from medicinal plants is a promising direction for new antibacterial treatments,. The purpose of this review is to summarize the verified data on the anti-QS properties of medicinal plants and the various mechanisms of their actions.