Review of ferroelectric hydroxyapatite and its application to biomedicine*

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22 Scopus citations


Hydroxyapatite (HA) is a major component of bone in humans and animals. Until about 10 years ago, it was considered to have a centrosymmetric crystal structure and could not contribute to the well-known piezoelectric effect in bone. This review describes the theoretical and experimental studies that showed that HA does have a non-centrosymmetric structure. Recent experiments have shown that HA exhibits piezoelectricity, pyroelectricity, and ferroelectricity. It has been made in the form of thick films and as space-charge electrets. It has an important biomedical application as an implant for bone cell attachment and growth.

Original languageEnglish
Pages (from-to)678-694
Number of pages17
JournalPhase Transitions
Issue number7-8
StatePublished - 2 Aug 2016


  • Hydroxyapatite
  • bone
  • ferroelectricity
  • piezoelectricity
  • pyroelectricity
  • space-charge

ASJC Scopus subject areas

  • Instrumentation
  • General Materials Science


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