Robustness of synthetic circadian clocks to multiple environmental changes

Lilia Gurevich; Rivka Cohen-Luria; Nathaniel Wagner; Gonen Ashkenasy

doi:10.1039/c5cc00098j

Robustness of synthetic circadian clocks to multiple environmental changes

Lilia Gurevich, Rivka Cohen-Luria, Nathaniel Wagner, Gonen Ashkenasy

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.

Original language	English
Pages (from-to)	5672-5675
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	26
DOIs	https://doi.org/10.1039/c5cc00098j
State	Published - 4 Apr 2015

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "Robustness of synthetic circadian clocks to multiple environmental changes",

abstract = "A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.",

author = "Lilia Gurevich and Rivka Cohen-Luria and Nathaniel Wagner and Gonen Ashkenasy",

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AU - Gurevich, Lilia

AU - Cohen-Luria, Rivka

AU - Wagner, Nathaniel

AU - Ashkenasy, Gonen

PY - 2015/4/4

Y1 - 2015/4/4

N2 - A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.

AB - A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.

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DO - 10.1039/c5cc00098j

M3 - Article

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VL - 51

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JO - Chemical Communications

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IS - 26

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Robustness of synthetic circadian clocks to multiple environmental changes

Abstract

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