Role of hydrogen bonding in cocrystals and coamorphous solids: indapamide as a case study

Suryanarayana Allu, Kuthuru Suresh, Geetha Bolla, M. K.Chaitanya Mannava, Ashwini Nangia

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

The stronger sulfonamide-pyridine (SO2NH2...N-Py) and sulfonamide-carboxamide (SO2NH2...O═C-NH) hydrogen bonds direct the formation of cocrystals, while the weaker sulfonamide-amine (SO2NH2...N-H) hydrogen bond results in coamorphous products. IDP-PIP and IDP-ARG coamorphous solids exhibit remarkable stability under accelerated conditions.

Original languageEnglish
Pages (from-to)2043-2048
Number of pages6
JournalCrystEngComm
Volume21
Issue number13
DOIs
StatePublished - 1 Jan 2019
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry
  • General Materials Science
  • Condensed Matter Physics

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