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Role of the Thymus in the Development of Immunocompetence of Embryonic Liver Cells in Vitro

  • T. Umiel
  • , A. Globerson
  • , R. Auerbach

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

The immunological competence of embryonic mouse liver cells was studied using the in vitro graft-versus-host system for assay. Embryonic liver cells did not have the capacity to induce splenomegaly when taken from embryos directly, nor did they acquire this capacity when cultivated as organ cultures for four to six days. The capacity to induce splenomegaly was acquired, however, when liver explants were cultivated for several days in combination with thymus tissue.

Original languageEnglish
Pages (from-to)598-600
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
Volume129
Issue number2
DOIs
StatePublished - 1 Jan 1968
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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