Ruthenium-catalyzed hydroarylation of anilides with alkynes: An efficient route to ortho -Alkenylated anilines

Rajendran Manikandan, Masilamani Jeganmohan

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

Acetanilides reacted with symmetrical as well as unsymmetrical alkynes in the presence of [{RuCl2(p-cymene)}2], pivalic acid, and AgSbF6 in iso-PrOH providing ortho-alkenylated acetanilides in a highly regio- and stereoselective manner. Later, ortho-alkenylated acetanilides were converted into ortho-alkenylated anilines in the presence of HCl.

Original languageEnglish
Pages (from-to)912-915
Number of pages4
JournalOrganic Letters
Volume16
Issue number3
DOIs
StatePublished - 7 Feb 2014
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Ruthenium-catalyzed hydroarylation of anilides with alkynes: An efficient route to ortho -Alkenylated anilines'. Together they form a unique fingerprint.

Cite this