Ruthenium(II)-Catalyzed Redox-Neutral Oxidative Cyclization of Benzimidates with Alkenes with Hydrogen Evolution

Rajendran Manikandan, Masilamani Tamizmani, Masilamani Jeganmohan

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

1H-Isoindoles and 2H-isoindoles are synthesized via a ruthenium-catalyzed oxidant-free cyclization of benzimidates with alkenes at room temperature with the liberation of H2. Later, 1H-isoindoles were converted into nitrogen-containing heterocycles. The proposed reaction mechanism was strongly supported by experimental evidence and DFT calculations.

Original languageEnglish
Pages (from-to)6678-6681
Number of pages4
JournalOrganic Letters
Volume19
Issue number24
DOIs
StatePublished - 15 Dec 2017
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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