Ruthenium(II)-Catalyzed Redox-Neutral Oxidative Cyclization of Benzimidates with Alkenes with Hydrogen Evolution

Rajendran Manikandan; Masilamani Tamizmani; Masilamani Jeganmohan

doi:10.1021/acs.orglett.7b03405

Ruthenium(II)-Catalyzed Redox-Neutral Oxidative Cyclization of Benzimidates with Alkenes with Hydrogen Evolution

Rajendran Manikandan, Masilamani Tamizmani, Masilamani Jeganmohan

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

1H-Isoindoles and 2H-isoindoles are synthesized via a ruthenium-catalyzed oxidant-free cyclization of benzimidates with alkenes at room temperature with the liberation of H₂. Later, 1H-isoindoles were converted into nitrogen-containing heterocycles. The proposed reaction mechanism was strongly supported by experimental evidence and DFT calculations.

Original language	English
Pages (from-to)	6678-6681
Number of pages	4
Journal	Organic Letters
Volume	19
Issue number	24
DOIs	https://doi.org/10.1021/acs.orglett.7b03405
State	Published - 15 Dec 2017
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/acs.orglett.7b03405

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abstract = "1H-Isoindoles and 2H-isoindoles are synthesized via a ruthenium-catalyzed oxidant-free cyclization of benzimidates with alkenes at room temperature with the liberation of H2. Later, 1H-isoindoles were converted into nitrogen-containing heterocycles. The proposed reaction mechanism was strongly supported by experimental evidence and DFT calculations.",

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AU - Jeganmohan, Masilamani

PY - 2017/12/15

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AB - 1H-Isoindoles and 2H-isoindoles are synthesized via a ruthenium-catalyzed oxidant-free cyclization of benzimidates with alkenes at room temperature with the liberation of H2. Later, 1H-isoindoles were converted into nitrogen-containing heterocycles. The proposed reaction mechanism was strongly supported by experimental evidence and DFT calculations.

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Ruthenium(II)-Catalyzed Redox-Neutral Oxidative Cyclization of Benzimidates with Alkenes with Hydrogen Evolution

Abstract

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UN SDGs

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