Saliva-controlled sputum culture (SSC) – A high value diagnostic tool for deep pulmonary infections

Inna Gitelman

doi:10.1016/j.mimet.2020.105986

Saliva-controlled sputum culture (SSC) – A high value diagnostic tool for deep pulmonary infections

Inna Gitelman

Department of Physiology and Cell Biology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A major obstacle to prompt diagnosis of fungal pulmonary infections is that deep sputum samples are scarce, yet are frequently rejected if they contain saliva. We show that including saliva controls unfailingly distinguishes oropharyngeal flora from pulmonary fungi, thus preserving valuable samples for analysis, expediting diagnoses and improving patient care.

Original language	English
Article number	105986
Journal	Journal of Microbiological Methods
Volume	179
DOIs	https://doi.org/10.1016/j.mimet.2020.105986
State	Published - 1 Dec 2020

Keywords

Aspergillosis
Deep fungal pulmonary infections
Early diagnosis
Improved outcomes
Optimization guidelines recommendations
Oropharyngeal flora contamination
Paired saliva~sputum cultures – the SSC protocol
Patient-assisted sputum collection
Sputum rejection

ASJC Scopus subject areas

Microbiology
Molecular Biology
Microbiology (medical)

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title = "Saliva-controlled sputum culture (SSC) – A high value diagnostic tool for deep pulmonary infections",

abstract = "A major obstacle to prompt diagnosis of fungal pulmonary infections is that deep sputum samples are scarce, yet are frequently rejected if they contain saliva. We show that including saliva controls unfailingly distinguishes oropharyngeal flora from pulmonary fungi, thus preserving valuable samples for analysis, expediting diagnoses and improving patient care.",

keywords = "Aspergillosis, Deep fungal pulmonary infections, Early diagnosis, Improved outcomes, Optimization guidelines recommendations, Oropharyngeal flora contamination, Paired saliva~sputum cultures – the SSC protocol, Patient-assisted sputum collection, Sputum rejection",

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AB - A major obstacle to prompt diagnosis of fungal pulmonary infections is that deep sputum samples are scarce, yet are frequently rejected if they contain saliva. We show that including saliva controls unfailingly distinguishes oropharyngeal flora from pulmonary fungi, thus preserving valuable samples for analysis, expediting diagnoses and improving patient care.

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KW - Early diagnosis

KW - Improved outcomes

KW - Optimization guidelines recommendations

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KW - Patient-assisted sputum collection

KW - Sputum rejection

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Saliva-controlled sputum culture (SSC) – A high value diagnostic tool for deep pulmonary infections

Abstract

Keywords

ASJC Scopus subject areas

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