Sarcopenia is associated with a greater incidence of delayed gastric emptying following pancreaticoduodenectomy

James Tankel, Amir Dagan, Elena Vainberg, Elad Boaz, Liel Mogilevsky, Irit Hadas, Petachia Reissman, Menahem Ben Haim

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background and aims: Sarcopenia is the degenerative loss of skeletal muscle and has been associated with a variety of post-operative complications. We propose sarcopenia is associated with delayed gastric emptying (DGE) following elective pancreaticoduodenectomy (PD). Methods: A retrospective analysis of a computerised database maintained in real time of all patients undergoing PD within our hepatobiliary unit was performed. The cross-sectional area of the psoas muscle at the upper border of L3 was calculated and corrected for patient height. The lowest quartile of gender specific groups was considered to be sarcopenic. Results: 61 patients were included, 32 male and 29 female of whom 8 from each group were sarcopenic (26.2%). Although the sarcopenic and non-sarcopenia groups were found to be comparable, significantly more sarcopenic patients were older (75 vs 64 years, p = 0.003), had a lower body mass index (21.9 vs 25.0 kg/m2, p = 0.003) and suffered from DGE (7/16 vs 8/45, p = 0.045). On multivariate analysis, these variables maintained their significance with DGE having an OR of 6.042 (p = 0.036). Conclusion: Sarcopenia is significantly associated with DGE, older age and lower BMI in this specific cohort of patients. Further research into the reversibility of this phenomenon is warranted.

Original languageEnglish
Pages (from-to)105-109
Number of pages5
JournalClinical Nutrition ESPEN
Volume27
DOIs
StatePublished - 1 Oct 2018
Externally publishedYes

Keywords

  • Complication
  • Delayed gastric emptying
  • Pancreaticoduodenectomy

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

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