Abstract
From the soft bodied coral Sarcophytum glaucum a crystalline compound-sarcophine (1), which is believed to be one of the repellents protecting the coral against predators, was isolated. The functional groups of 1 have been deduced from detailed NMR study and the whole molecular structure has been determined by a single-crystal 3-dimensional X-ray diffraction study proceeding from direct methods. The compound crystallizes in orthorhombic crystals, space group P212121, and there are four molecules in each unit cell of dimensions a = 12·429(3), b = 13·766(3) and c = 10·750(1). The structure was found to be a new epoxy cembranolide. The mass spectrum and CD of 1 and several simple derivatives as well as the conformation of 1 in solution are discussed.
Original language | English |
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Pages (from-to) | 2817-2824 |
Number of pages | 8 |
Journal | Tetrahedron |
Volume | 30 |
Issue number | 16 |
DOIs | |
State | Published - 1 Jan 1974 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry