Screening South Indian Medicinal Plants for Antifungal Activity Against Cutaneous Pathogens

A. Vonshak; O. Barazani; P. Sathiyamoorthy; R. Shalev; D. Vardy; A. Golan-Goldhirsh

doi:10.1002/ptr.1399

Screening South Indian Medicinal Plants for Antifungal Activity Against Cutaneous Pathogens

A. Vonshak, O. Barazani, P. Sathiyamoorthy, R. Shalev, D. Vardy, A. Golan-Goldhirsh

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Abstract

In this study, twenty-eight South Indian medicinal plants were screened for their anti-fungal activity against six species of fungi (Trichophyton mentagrophytes, T. rubrum, T. soudanense, Candida albicans, Torulopsis glabrata, and C. krusei). Three plant species extracts, Celastrus paniculatus, Eriodendron anfractuosum and Ficus glomerata showed inhibitory activity. An aqueous extract of galls of Terminalia chebula showed inhibitory effects on three dermatophytes (Trichophyton spp.) and three yeasts (Candida spp.). Seeds extract of T. chebula inhibited only the growth of T. glabrata. An aqueous extract of T. chebula showed inhibitory effects higher than those measured in ethanol extracts. It is therefore suggested that tannins are plausible candidates for the anti-dermatophytic effects of T. chebula. Chebulinic acid, a known tannin of T. chebula was tested and found not inhibitory, thus a search for the active compound is needed.

Original language	English
Pages (from-to)	1123-1125
Number of pages	3
Journal	Phytotherapy Research
Volume	17
Issue number	9
DOIs	https://doi.org/10.1002/ptr.1399
State	Published - 1 Nov 2003

Keywords

Anti-fungal
Indian medicinal plants
Skin
Terminalia chebula

ASJC Scopus subject areas

Pharmacology

Access to Document

10.1002/ptr.1399

Cite this

@article{51cf936b2557403a8a9c7fae23658695,

title = "Screening South Indian Medicinal Plants for Antifungal Activity Against Cutaneous Pathogens",

abstract = "In this study, twenty-eight South Indian medicinal plants were screened for their anti-fungal activity against six species of fungi (Trichophyton mentagrophytes, T. rubrum, T. soudanense, Candida albicans, Torulopsis glabrata, and C. krusei). Three plant species extracts, Celastrus paniculatus, Eriodendron anfractuosum and Ficus glomerata showed inhibitory activity. An aqueous extract of galls of Terminalia chebula showed inhibitory effects on three dermatophytes (Trichophyton spp.) and three yeasts (Candida spp.). Seeds extract of T. chebula inhibited only the growth of T. glabrata. An aqueous extract of T. chebula showed inhibitory effects higher than those measured in ethanol extracts. It is therefore suggested that tannins are plausible candidates for the anti-dermatophytic effects of T. chebula. Chebulinic acid, a known tannin of T. chebula was tested and found not inhibitory, thus a search for the active compound is needed.",

keywords = "Anti-fungal, Indian medicinal plants, Skin, Terminalia chebula",

author = "A. Vonshak and O. Barazani and P. Sathiyamoorthy and R. Shalev and D. Vardy and A. Golan-Goldhirsh",

year = "2003",

month = nov,

day = "1",

doi = "10.1002/ptr.1399",

language = "English",

volume = "17",

pages = "1123--1125",

journal = "Phytotherapy Research",

issn = "0951-418X",

publisher = "John Wiley and Sons Ltd",

number = "9",

}

TY - JOUR

T1 - Screening South Indian Medicinal Plants for Antifungal Activity Against Cutaneous Pathogens

AU - Vonshak, A.

AU - Barazani, O.

AU - Sathiyamoorthy, P.

AU - Shalev, R.

AU - Vardy, D.

AU - Golan-Goldhirsh, A.

PY - 2003/11/1

Y1 - 2003/11/1

N2 - In this study, twenty-eight South Indian medicinal plants were screened for their anti-fungal activity against six species of fungi (Trichophyton mentagrophytes, T. rubrum, T. soudanense, Candida albicans, Torulopsis glabrata, and C. krusei). Three plant species extracts, Celastrus paniculatus, Eriodendron anfractuosum and Ficus glomerata showed inhibitory activity. An aqueous extract of galls of Terminalia chebula showed inhibitory effects on three dermatophytes (Trichophyton spp.) and three yeasts (Candida spp.). Seeds extract of T. chebula inhibited only the growth of T. glabrata. An aqueous extract of T. chebula showed inhibitory effects higher than those measured in ethanol extracts. It is therefore suggested that tannins are plausible candidates for the anti-dermatophytic effects of T. chebula. Chebulinic acid, a known tannin of T. chebula was tested and found not inhibitory, thus a search for the active compound is needed.

AB - In this study, twenty-eight South Indian medicinal plants were screened for their anti-fungal activity against six species of fungi (Trichophyton mentagrophytes, T. rubrum, T. soudanense, Candida albicans, Torulopsis glabrata, and C. krusei). Three plant species extracts, Celastrus paniculatus, Eriodendron anfractuosum and Ficus glomerata showed inhibitory activity. An aqueous extract of galls of Terminalia chebula showed inhibitory effects on three dermatophytes (Trichophyton spp.) and three yeasts (Candida spp.). Seeds extract of T. chebula inhibited only the growth of T. glabrata. An aqueous extract of T. chebula showed inhibitory effects higher than those measured in ethanol extracts. It is therefore suggested that tannins are plausible candidates for the anti-dermatophytic effects of T. chebula. Chebulinic acid, a known tannin of T. chebula was tested and found not inhibitory, thus a search for the active compound is needed.

KW - Anti-fungal

KW - Indian medicinal plants

KW - Skin

KW - Terminalia chebula

UR - http://www.scopus.com/inward/record.url?scp=0242331628&partnerID=8YFLogxK

U2 - 10.1002/ptr.1399

DO - 10.1002/ptr.1399

M3 - Article

AN - SCOPUS:0242331628

SN - 0951-418X

VL - 17

SP - 1123

EP - 1125

JO - Phytotherapy Research

JF - Phytotherapy Research

IS - 9

ER -

Screening South Indian Medicinal Plants for Antifungal Activity Against Cutaneous Pathogens

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this