Abstract
Inositol levels measured in postmortem brain of unipolar, bipolar and schizophrenic patients, suicide victims and normal controls showed no difference in scyllo-inositol levels in frontal or occipital cortex between any of the groups. We could not replicate previous reports of low myo-inositol levels in the frontal cortex of unipolar, bipolar and schizophrenic patients and suicide victims. There was no correlation between myo-inositol levels and estimated chlorpromazine equivalents in neuroleptic-treated subjects, and no effect of chronic haloperidol treatment on rat brain myo-inositol levels.
| Original language | English |
|---|---|
| Pages (from-to) | 603-607 |
| Number of pages | 5 |
| Journal | Journal of Neural Transmission |
| Volume | 107 |
| Issue number | 5 |
| DOIs | |
| State | Published - 1 Jan 2000 |
Keywords
- Bipolar patients
- Myo-inositol
- Neuroleptic treatment
- Post-mortem brain
- Schizophrenic patients
- Scyllo-inositol
- Suicide victims
- Unipolar patients
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Psychiatry and Mental health
- Biological Psychiatry
