Second-trimester membrane rupture: Abortion induced with prostaglandin E 2 after oxytocin failure

Jack Atad; Mordechai Hallak; Oren Fruchter; Jacob Borenstein; Haim Abramovici

Second-trimester membrane rupture: Abortion induced with prostaglandin E ₂ after oxytocin failure

Jack Atad, Mordechai Hallak, Oren Fruchter, Jacob Borenstein, Haim Abramovici

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

OBJECTIVE: To test an effective method of terminating second-trimester pregnancy with ruptured membranes in women who fail to abort from an oxytocin infusion. STUDY DESIGN: Five patients with rupture of membranes during the second trimester of pregnancy and failed to abort using the traditional method of intravenous oxytocin infusion were treated with intrauterine instillation of prostaglandin E ₂ (PGE ₂) solution through a double-balloon device. RESULTS: All five patients aborted within 8.8 ± 4.5 hours from the beginning of PGE ₂ instillation. No major complications occurred. The only side effect was short-duration pyrexia (less than 48 hours). CONCLUSION: Use of the double-balloon device and intrauterine instillation of PGE ₂ was effective for termination of pregnancy in patients with rupture of membranes who do not respond to oxytocin.

Original language	English
Pages (from-to)	581-584
Number of pages	4
Journal	The Journal of reproductive medicine
Volume	42
Issue number	9
State	Published - 1 Sep 1997
Externally published	Yes

Keywords

Abortion, induced
Fetal membranes, premature rupture
Oxytocin
Pregnancy trimester, second
Prostaglandin E, synthetic

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

Cite this

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title = "Second-trimester membrane rupture: Abortion induced with prostaglandin E 2 after oxytocin failure",

abstract = "OBJECTIVE: To test an effective method of terminating second-trimester pregnancy with ruptured membranes in women who fail to abort from an oxytocin infusion. STUDY DESIGN: Five patients with rupture of membranes during the second trimester of pregnancy and failed to abort using the traditional method of intravenous oxytocin infusion were treated with intrauterine instillation of prostaglandin E 2 (PGE 2) solution through a double-balloon device. RESULTS: All five patients aborted within 8.8 ± 4.5 hours from the beginning of PGE 2 instillation. No major complications occurred. The only side effect was short-duration pyrexia (less than 48 hours). CONCLUSION: Use of the double-balloon device and intrauterine instillation of PGE 2 was effective for termination of pregnancy in patients with rupture of membranes who do not respond to oxytocin.",

keywords = "Abortion, induced, Fetal membranes, premature rupture, Oxytocin, Pregnancy trimester, second, Prostaglandin E, synthetic",

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T1 - Second-trimester membrane rupture

T2 - Abortion induced with prostaglandin E 2 after oxytocin failure

AU - Atad, Jack

AU - Hallak, Mordechai

AU - Fruchter, Oren

AU - Borenstein, Jacob

AU - Abramovici, Haim

PY - 1997/9/1

Y1 - 1997/9/1

N2 - OBJECTIVE: To test an effective method of terminating second-trimester pregnancy with ruptured membranes in women who fail to abort from an oxytocin infusion. STUDY DESIGN: Five patients with rupture of membranes during the second trimester of pregnancy and failed to abort using the traditional method of intravenous oxytocin infusion were treated with intrauterine instillation of prostaglandin E 2 (PGE 2) solution through a double-balloon device. RESULTS: All five patients aborted within 8.8 ± 4.5 hours from the beginning of PGE 2 instillation. No major complications occurred. The only side effect was short-duration pyrexia (less than 48 hours). CONCLUSION: Use of the double-balloon device and intrauterine instillation of PGE 2 was effective for termination of pregnancy in patients with rupture of membranes who do not respond to oxytocin.

AB - OBJECTIVE: To test an effective method of terminating second-trimester pregnancy with ruptured membranes in women who fail to abort from an oxytocin infusion. STUDY DESIGN: Five patients with rupture of membranes during the second trimester of pregnancy and failed to abort using the traditional method of intravenous oxytocin infusion were treated with intrauterine instillation of prostaglandin E 2 (PGE 2) solution through a double-balloon device. RESULTS: All five patients aborted within 8.8 ± 4.5 hours from the beginning of PGE 2 instillation. No major complications occurred. The only side effect was short-duration pyrexia (less than 48 hours). CONCLUSION: Use of the double-balloon device and intrauterine instillation of PGE 2 was effective for termination of pregnancy in patients with rupture of membranes who do not respond to oxytocin.

KW - Abortion, induced

KW - Fetal membranes, premature rupture

KW - Oxytocin

KW - Pregnancy trimester, second

KW - Prostaglandin E, synthetic

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Second-trimester membrane rupture: Abortion induced with prostaglandin E ₂ after oxytocin failure

Abstract

Keywords

ASJC Scopus subject areas

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