SELECTIVE INCORPORATION OF 5-HYROXYTRYPTOPHAN INTO PROTEINS IN MAMMALIAN CELLS.

Schultz Peter; Alfonta Lital; Zhang Zhiwen

SELECTIVE INCORPORATION OF 5-HYROXYTRYPTOPHAN INTO PROTEINS IN MAMMALIAN CELLS.

Schultz Peter (Inventor), Alfonta Lital (Inventor), Zhang Zhiwen (Inventor)

Department of Biotechnology Engineering

Research output: Patent

Abstract

This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation.

Original language	English
Patent number	MXPA06006868
IPC	C12N 9/ 00 A I
Priority date	16/12/04
State	Published - 21 Mar 2007

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title = "SELECTIVE INCORPORATION OF 5-HYROXYTRYPTOPHAN INTO PROTEINS IN MAMMALIAN CELLS.",

abstract = "This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation.",

author = "Schultz Peter and Alfonta Lital and Zhang Zhiwen",

year = "2007",

month = mar,

day = "21",

language = "English",

type = "Patent",

note = "MXPA06006868; C12N 9/ 00 A I",

}

TY - PAT

T1 - SELECTIVE INCORPORATION OF 5-HYROXYTRYPTOPHAN INTO PROTEINS IN MAMMALIAN CELLS.

AU - Peter, Schultz

AU - Lital, Alfonta

AU - Zhiwen, Zhang

PY - 2007/3/21

Y1 - 2007/3/21

N2 - This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation.

AB - This invention provides methods and compositions for incorporation of an unnatural amino acid into a peptide using an orthogonal aminoacyl tRNA synthetase/tRNA pair. In particular, an orthogonal pair is provided to incorporate 5-hydroxy-L-tryptophan in a position encoded by an opal mutation.

M3 - Patent

M1 - MXPA06006868

ER -

SELECTIVE INCORPORATION OF 5-HYROXYTRYPTOPHAN INTO PROTEINS IN MAMMALIAN CELLS.

Abstract

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