Self-programmed nanovesicle to nanofiber transformation of a dipeptide appended bolaamphiphile and its dose dependent cytotoxic behaviour

Indrajit Maity; Hamendra S. Parmar; Dnyaneshwar B. Rasale; Apurba K. Das

doi:10.1039/c4tb00365a

Self-programmed nanovesicle to nanofiber transformation of a dipeptide appended bolaamphiphile and its dose dependent cytotoxic behaviour

Indrajit Maity, Hamendra S. Parmar, Dnyaneshwar B. Rasale, Apurba K. Das

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Nanostructural transition of a small peptide bolaamphiphile via molecular self-assembly is a challenging task. Here, we report the self-programmed morphological transformation from nanovesicles to nanofibers of a smart peptide bolaamphiphile in its self-assembling hydrogel state. The nanostructural transition occurs based on the structural continuity of the β-sheet structures. Spectroscopic studies confirmed the different molecular arrangements of the two different nanostructures. Furthermore, the smart bolaamphiphile shows a dose-dependent cytotoxicity and cell-proliferation behaviour. This journal is

Original language	English
Pages (from-to)	5272-5279
Number of pages	8
Journal	Journal of Materials Chemistry B
Volume	2
Issue number	32
DOIs	https://doi.org/10.1039/c4tb00365a
State	Published - 28 Aug 2014
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
Biomedical Engineering
General Materials Science

Access to Document

10.1039/c4tb00365a

Cite this

@article{6382a4567c35430fb1acb4801be610bf,

title = "Self-programmed nanovesicle to nanofiber transformation of a dipeptide appended bolaamphiphile and its dose dependent cytotoxic behaviour",

abstract = "Nanostructural transition of a small peptide bolaamphiphile via molecular self-assembly is a challenging task. Here, we report the self-programmed morphological transformation from nanovesicles to nanofibers of a smart peptide bolaamphiphile in its self-assembling hydrogel state. The nanostructural transition occurs based on the structural continuity of the β-sheet structures. Spectroscopic studies confirmed the different molecular arrangements of the two different nanostructures. Furthermore, the smart bolaamphiphile shows a dose-dependent cytotoxicity and cell-proliferation behaviour. This journal is",

author = "Indrajit Maity and Parmar, {Hamendra S.} and Rasale, {Dnyaneshwar B.} and Das, {Apurba K.}",

year = "2014",

month = aug,

day = "28",

doi = "10.1039/c4tb00365a",

language = "English",

volume = "2",

pages = "5272--5279",

journal = "Journal of Materials Chemistry B",

issn = "2050-7518",

publisher = "Royal Society of Chemistry",

number = "32",

}

TY - JOUR

T1 - Self-programmed nanovesicle to nanofiber transformation of a dipeptide appended bolaamphiphile and its dose dependent cytotoxic behaviour

AU - Maity, Indrajit

AU - Parmar, Hamendra S.

AU - Rasale, Dnyaneshwar B.

AU - Das, Apurba K.

PY - 2014/8/28

Y1 - 2014/8/28

N2 - Nanostructural transition of a small peptide bolaamphiphile via molecular self-assembly is a challenging task. Here, we report the self-programmed morphological transformation from nanovesicles to nanofibers of a smart peptide bolaamphiphile in its self-assembling hydrogel state. The nanostructural transition occurs based on the structural continuity of the β-sheet structures. Spectroscopic studies confirmed the different molecular arrangements of the two different nanostructures. Furthermore, the smart bolaamphiphile shows a dose-dependent cytotoxicity and cell-proliferation behaviour. This journal is

AB - Nanostructural transition of a small peptide bolaamphiphile via molecular self-assembly is a challenging task. Here, we report the self-programmed morphological transformation from nanovesicles to nanofibers of a smart peptide bolaamphiphile in its self-assembling hydrogel state. The nanostructural transition occurs based on the structural continuity of the β-sheet structures. Spectroscopic studies confirmed the different molecular arrangements of the two different nanostructures. Furthermore, the smart bolaamphiphile shows a dose-dependent cytotoxicity and cell-proliferation behaviour. This journal is

UR - http://www.scopus.com/inward/record.url?scp=84904745048&partnerID=8YFLogxK

U2 - 10.1039/c4tb00365a

DO - 10.1039/c4tb00365a

M3 - Article

AN - SCOPUS:84904745048

SN - 2050-7518

VL - 2

SP - 5272

EP - 5279

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 32

ER -

Self-programmed nanovesicle to nanofiber transformation of a dipeptide appended bolaamphiphile and its dose dependent cytotoxic behaviour

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this