Abstract
A 6‐month‐old child with familial hemophagocytic lymphohistiocytosis (FHL) experienced early sequential pneumonia due to respiratory syncytial virus (RSV) and cytomegalovirus (CMV) following bone marrow transplantation (BMT). The patient was deficient in natural killer (NK) cell activity (as found frequently in patients with FHL), and this risk factor may have played a major role in the concomitant infection by the two viral pathogens. Rapid diagnostic methods for both viruses are essential and early specific treatment may serve to ameliorate RSV‐ and CMV‐induced lung injury in these life‐threatening infections. © 1995 Wiley‐Liss, Inc.
Original language | English |
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Pages (from-to) | 169-171 |
Number of pages | 3 |
Journal | Journal of Medical Virology |
Volume | 46 |
Issue number | 2 |
DOIs | |
State | Published - 1 Jan 1995 |
Externally published | Yes |
Keywords
- bone marrow transplantation
- cytomegalovirus
- familial hemophagocytic lymphohistiocytosis
- interstitial pneumonia
- respiratory syncytial virus
ASJC Scopus subject areas
- Virology
- Infectious Diseases