Serum 17-beta-estradiol and testosterone levels in asymptomatic hyperuricaemic men

R. Rosen, Y. Tomer, R. Carel, A. Weinberger

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations

    Abstract

    Low levels of oestrogen, FSH and LH in serum have been reported in patients with gout. The mechanism by which sex hormones affect the development of gout is unknown, but some investigators believe that it is related to the influence of oestrogens on serum uric acid levels. We studied the relationship between serum uric acid and 17 beta oestradiol (ES) levels in asymptomatic hyperuricaemic (ASH) men in order to test the hypothesis that low ES levels are associated with hyperuricaemia. Thirty-eight men with asymptomatic hyperuricaemia (ASH) were selected from a population of healthy individuals undergoing periodical multiphasic health examinations. After adjusting for the differences in albumin levels between the two groups, no significant difference in serum ES level was found. The serum testosterone levels were similar in both groups. These findings suggest that there is no difference in the sex hormone profiles between asymptomatic hyperuricaemic and normouricaemic men.

    Original languageEnglish
    Pages (from-to)219-223
    Number of pages5
    JournalClinical Rheumatology
    Volume13
    Issue number2
    DOIs
    StatePublished - 1 Jun 1994

    Keywords

    • Gout
    • Hyperuricaemia
    • Sex Hormones

    ASJC Scopus subject areas

    • Rheumatology

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