Severe jaundice in a gunshot casualty due to the coexistence of Dubin- Johnson and glucose-6-phosphate dehydrogenase deficiency

Doron Zamir, G. Groisman, C. Zamir, E. Sternberg, M. Iuchtman, R. Alfisi, P. Weiner

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We report an unusual case of a 21-year-old man who was shot in his abdomen in the course of a robbery. He was previously diagnosed as glucose- 6-phosphate dehydrogenase deficient. Mild icterus was noticed on admission to the emergency room. Exploratory laparotomy revealed a perforated ileal loop that was resected, and because the liver color was greenish black, a liver biopsy was performed during the operation. After operation the patient went through a severe icteric state that resolved spontaneously within a few days. Urinary coproporphyrin levels, along with compatible liver biopsy, confirmed the diagnosis of Dubin-Johnson disease. Severe hyperbilirubinemia after an abdominal injury is uncommon and is usually due to either a biliary duct injury or iatrogenic injury. This case presents an unusual cause of severe postoperative jaundice due to the rare coexistence of two inherited disorders.

Original languageEnglish
Pages (from-to)383-385
Number of pages3
JournalJournal of Clinical Gastroenterology
Volume28
Issue number4
DOIs
StatePublished - 1 Jun 1999
Externally publishedYes

Keywords

  • Dubin-Johnson
  • Explorative laparotomy
  • G6PD deficiency

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