Severe ovarian hyperstimulation syndrome despite low plasma oestrogen concentrations in a hypogonadotrophic, hypogonadal patient

Tally Levy, Raoul Orvieto, Roy Homburg, Dan Peleg, Arie Dekel, Zion Ben-Rafael

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Ovarian hyperstimulation syndrome (OHSS) is the most serious, life-threatening, iatrogenic complication of ovulation induction. The importance of excessive oestradiol concentrations on the day of human chorionic gonadotrophin (HCG) administration as a predictor and factor in the pathophysiology of OHSS has been extensively studied and discussed. We present the case report of a woman with hypogonadotrophic hypogonadism who developed severe OHSS during ovulation induction with urinary human follicle stimulating hormone (FSH) and HCG in the presence of low circulating oestradiol concentrations. The implication of FSH treatment and complications in hypogonadotrophic hypogonadal patients, and the role of preovulatory oestradiol concentrations in the prediction of OHSS, are discussed.

Original languageEnglish
Pages (from-to)1177-1179
Number of pages3
JournalHuman Reproduction
Volume11
Issue number6
DOIs
StatePublished - 1 Jan 1996
Externally publishedYes

Keywords

  • Hypogonadotrophic hypogonadism
  • OHSS
  • Oestradiol concentration
  • Prediction

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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