TY - JOUR
T1 - Short-Coupled Idiopathic Ventricular Fibrillation
T2 - A Literature Review With Extended Follow-Up
AU - Belhassen, Bernard
AU - Tovia-Brodie, Oholi
N1 - Funding Information:
The authors sincerely thank all authors or coauthors who provided us with additional information dealing with their published papers: USA: Joshua Moss, MD; Melvin Scheinman, MD; Pattara Rattanawong, MD; Srivathsan Komandoor, MD; Norman Wang MD; Elad Anter, MD; Subramaniam Krishnan, MD; Johannes vonAlvensleben, MD; Jason Chinitz, MD; Lior Jankelson, MD; Alexander Mazur, MD; Walid Saliba MD; Reginald Ho, MD; Babak Nazer, MD; Hussein Rabah, MD; Mario Gonzalez, MD; Nabil El-Sherif, MD; Soufian Almahameed, MD; Japan: Minoru Horie, MD; Akihito Nogami, MD; Satoshi Nagase, MD; Seiji Takatsuki, MD; Takeshi Tsuchiya, MD; Shun Kohsaka, MD; Tsuyoshi Shiga, MD; Yuji Nakazato, MD; Yoshiyasu Aizawa, MD; Keita Masuda, MD; Yoshihiro Harano, MD; France: Lucien Muresan, MD; Zahia Touat-Hamici, PHD; Jean Luc Pasquié, MD; Philippe Chevalier, MD; United Kingdom: Pier Lambiase, MD; Claire Martin, MD; Magdi Saba, MD; Arthur Yue, MD; Italy: Marco Zardini, MD; Giulio Conte, MD; Giuseppe Allocca, MD; Belgium: Dominique Blommaert, MD; Mr Fabien Dormal; Luc Jordaens, MD; Brazil: Mauricio Scanavacca, MD; Muhieddine Chokr, MD; Netherlands: Paul Knops, MD; Raymond Tukkie, MD; Germany: Johannes Steinfurt, MD; Christopher Reithmann, MD; Boris Rudic, MD; Rainer Schimpf, MD; Sweden: Romeo Samo Ayou, MD; Kristina Herman Haugaa, MD; Australia: Raymond Sy, MD; India: Nitish Naik, MD; Austria: Bernhard Strohmer, MD; South Korea: Jong Sung Park, MD; Spain: Javier Garcia Hernandez, MD; Czechia: Martin Kleissner, MD; Canada: Mehrdad Golian, MD; Greece: Iannis-John Chiladakis, MD; and Poland: Alicja Dabrowska-Kugacka, MD.
Publisher Copyright:
© 2022 American College of Cardiology Foundation
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Idiopathic ventricular fibrillation is responsible for approximately 5%-7% of cases of aborted cardiac arrest. Recent studies have shown that short-coupled ventricular premature complexes are present at the onset of idiopathic ventricular fibrillation in 6.6%-17% of patients. The present review provided information on 86 patients with short-coupled malignant ventricular arrhythmias that were reported as case reports or small patient series during the last 70 years. In 75% of the 81 cases published during the last 40 years, extended information and follow-up (from 2.63 ± 4.5 years to 10.67 ± 7.8 years; P < 0.001, between the original publication to the latest update) could be obtained from the authors. The review shows that short-coupled malignant ventricular arrhythmias occurred almost equally in males and females, at the mean age of 40 years. A tendency for later occurrence of the arrhythmia by 4 years was observed in females. A prior history of syncope was noted in 45.3% of the patients, whereas arrhythmic storm occurred in 42% at presentation. The most common mode of revelation of short-coupled malignant ventricular arrhythmias was syncope (53.5%), followed by aborted cardiac arrest (26.7%) and recurrent arrhythmic event after prior implantable-cardioverter defibrillator implantation for idiopathic ventricular fibrillation (17.4%). For the first time, short-coupled malignant arrhythmias exhibiting “not-so-short” coupling intervals (≥350 milliseconds) were found in a significant proportion of patients (17.4%). During long-term follow-up, quinidine yielded a slightly higher success rate in arrhythmia control than ablation. Larger studies are necessary to assess the best strategy for the management of this potentially lethal arrhythmia.
AB - Idiopathic ventricular fibrillation is responsible for approximately 5%-7% of cases of aborted cardiac arrest. Recent studies have shown that short-coupled ventricular premature complexes are present at the onset of idiopathic ventricular fibrillation in 6.6%-17% of patients. The present review provided information on 86 patients with short-coupled malignant ventricular arrhythmias that were reported as case reports or small patient series during the last 70 years. In 75% of the 81 cases published during the last 40 years, extended information and follow-up (from 2.63 ± 4.5 years to 10.67 ± 7.8 years; P < 0.001, between the original publication to the latest update) could be obtained from the authors. The review shows that short-coupled malignant ventricular arrhythmias occurred almost equally in males and females, at the mean age of 40 years. A tendency for later occurrence of the arrhythmia by 4 years was observed in females. A prior history of syncope was noted in 45.3% of the patients, whereas arrhythmic storm occurred in 42% at presentation. The most common mode of revelation of short-coupled malignant ventricular arrhythmias was syncope (53.5%), followed by aborted cardiac arrest (26.7%) and recurrent arrhythmic event after prior implantable-cardioverter defibrillator implantation for idiopathic ventricular fibrillation (17.4%). For the first time, short-coupled malignant arrhythmias exhibiting “not-so-short” coupling intervals (≥350 milliseconds) were found in a significant proportion of patients (17.4%). During long-term follow-up, quinidine yielded a slightly higher success rate in arrhythmia control than ablation. Larger studies are necessary to assess the best strategy for the management of this potentially lethal arrhythmia.
KW - ablation
KW - idiopathic ventricular fibrillation
KW - quinidine
KW - short-coupled ventricular arrhythmias
UR - http://www.scopus.com/inward/record.url?scp=85130556478&partnerID=8YFLogxK
U2 - 10.1016/j.jacep.2022.04.013
DO - 10.1016/j.jacep.2022.04.013
M3 - Review article
C2 - 35597766
AN - SCOPUS:85130556478
SN - 2405-5018
VL - 8
SP - 918
EP - 936
JO - JACC: Clinical Electrophysiology
JF - JACC: Clinical Electrophysiology
IS - 7
ER -