Abstract
The present invention relates to short peptides based on the amino acids sequence of the N-terminal domain of the human mitochondrial protein voltage-dependent anion channel 1 (VDAC) and to peptide conjugates having a cell permeability enhancing moiety. The peptides, peptide conjugates and pharmaceutical compositions containing them are useful for treating diseases characterized by cell hyperproliferation or resistance to cell death and in particular, cancer.
| Original language | English |
|---|---|
| Patent number | US2016176937 |
| IPC | C07K 14/ 435 A I |
| Priority date | 24/07/14 |
| State | Published - 23 Jun 2016 |