Abstract
The present invention relates to short peptides based on the amino acids sequence of the N-terminal domain of the human mitochondrial protein voltage-dependent anion channel 1 (VDAC) and to peptide conjugates further comprising a cell permeability enhancing moiety. The peptides, peptide conjugates and pharmaceutical composition comprising same are useful for treating diseases characterized by cell hyperproliferation or resistance to cell death, particularly cancer.
| Original language | English |
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| Patent number | WO2015011711 |
| IPC | C07K 19/ 00 A I |
| Priority date | 25/07/13 |
| State | Published - 29 Jan 2015 |