Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

Eli Hershkovitz; Ester Leiberman; Yehuda Litnony; Shraga Shany; Moshe Phillip

doi:10.1159/000184975

Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

Eli Hershkovitz, Ester Leiberman, Yehuda Litnony, Shraga Shany, Moshe Phillip

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

Original language	English
Pages (from-to)	38-40
Number of pages	3
Journal	Hormone Research in Paediatrics
Volume	46
Issue number	1
DOIs	https://doi.org/10.1159/000184975
State	Published - 1 Jan 1996
Externally published	Yes

Keywords

Growth hormone
Lipoprotein (a)
Short children

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000184975

Cite this

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title = "Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency",

abstract = "We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.",

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author = "Eli Hershkovitz and Ester Leiberman and Yehuda Litnony and Shraga Shany and Moshe Phillip",

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doi = "10.1159/000184975",

language = "English",

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journal = "Hormone Research in Paediatrics",

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T1 - Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

AU - Hershkovitz, Eli

AU - Leiberman, Ester

AU - Litnony, Yehuda

AU - Shany, Shraga

AU - Phillip, Moshe

PY - 1996/1/1

Y1 - 1996/1/1

N2 - We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

AB - We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

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KW - Lipoprotein (a)

KW - Short children

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DO - 10.1159/000184975

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SP - 38

EP - 40

JO - Hormone Research in Paediatrics

JF - Hormone Research in Paediatrics

SN - 1663-2818

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Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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