Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

Eli Hershkovitz; Ester Leiberman; Yehuda Litnony; Shraga Shany; Moshe Phillip

doi:10.1159/000184975

Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

Eli Hershkovitz, Ester Leiberman, Yehuda Litnony, Shraga Shany, Moshe Phillip

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

Original language	English
Pages (from-to)	38-40
Number of pages	3
Journal	Hormone Research in Paediatrics
Volume	46
Issue number	1
DOIs	https://doi.org/10.1159/000184975
State	Published - 1 Jan 1996
Externally published	Yes

Keywords

Growth hormone
Lipoprotein (a)
Short children

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000184975

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title = "Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency",

abstract = "We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.",

keywords = "Growth hormone, Lipoprotein (a), Short children",

author = "Eli Hershkovitz and Ester Leiberman and Yehuda Litnony and Shraga Shany and Moshe Phillip",

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doi = "10.1159/000184975",

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T1 - Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

AU - Hershkovitz, Eli

AU - Leiberman, Ester

AU - Litnony, Yehuda

AU - Shany, Shraga

AU - Phillip, Moshe

PY - 1996/1/1

Y1 - 1996/1/1

N2 - We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

AB - We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

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KW - Lipoprotein (a)

KW - Short children

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SP - 38

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JO - Hormone Research in Paediatrics

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SN - 1663-2818

IS - 1

ER -

Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

Abstract

Keywords

UN SDGs

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