Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency

Eli Hershkovitz, Ester Leiberman, Yehuda Litnony, Shraga Shany, Moshe Phillip

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

We investigated the short-term effect of GH (0.1 IU/kg/day) on serum lipoprotein (a) [Lp(a)] in 8 normal short children aged 6-12 years. GH increased serum Lp(a) concentrations in all the children studied. An increase to 107 � 5, 161.6 � 14.7 and 152.5 � 18.5%(mean � SE) of baseline levels was observed after 2 (p = NS), 6 (p < 0.01) and 12 weeks (p < 0.05), respectively. Our results suggest that GH therapy may pose a significant influence on Lp(a) serum levels in non-GH-deficient short children.

Original languageEnglish
Pages (from-to)38-40
Number of pages3
JournalHormone Research in Paediatrics
Volume46
Issue number1
DOIs
StatePublished - 1 Jan 1996
Externally publishedYes

Keywords

  • Growth hormone
  • Lipoprotein (a)
  • Short children

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