Similarities between Neuropathic Pruritus sites and lichen simplex chronicus sites

Arnon D. Cohen, Israel D. Andrews, Evgeny Medvedovsky, Roni Peleg, Daniel A. Vardy

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations


    Background: Localized itch of non-pruritoceptive origin is often neuropathic and may be referred to as neuropathic itch syndrome.objectives: To describe the results of nerve conduction studies in patients with anogenital pruritus, brachioradial pruritus and scalp dysesthesia, and compare these sites to typical sites of lichen simplex chronicus (LSC). methods: The study summarizes previously published data combined with unpublished data of patients with scalp dysesthesia. Nerve conduction studies included measurements of distal sensory and motor latency, conduction velocity and F-responses. results: A neuropathy was demonstrated in 29 of 36 patients with anogenital pruritus (80.5%), 8/14 with brachioradial pruritus (57.1%) and 4/9 with scalp dysesthesia (44.4%). The typical sites overlapped with some but not all LSC sites. conclusions: A considerable proportion of patients with brachioradial pruritus, anogenital pruritus and scalp dys-esthesia have abnormal nerve conduction fndings, suggesting a neuropathic origin. The skin sites overlap with some common LSC sites, suggesting that in some cases of LSC a local neuropathy could be a possible cause.

    Original languageEnglish
    Pages (from-to)88-90
    Number of pages3
    JournalIsrael Medical Association Journal
    Issue number2
    StatePublished - 1 Feb 2014


    • Anogenital pruritus
    • Brachioradial pruritus
    • Lichen simplex chronicus (LSC)
    • Neuropathic pruritus

    ASJC Scopus subject areas

    • Medicine (all)


    Dive into the research topics of 'Similarities between Neuropathic Pruritus sites and lichen simplex chronicus sites'. Together they form a unique fingerprint.

    Cite this