Simultaneous indocyanine green and fluorescein angiography in retinal pigment epithelium tear using the confocal scanning laser ophthalmoscope

R Axer-Siegel, H Lichter, I Rosenblatt, E Priel, Y Yassur, D Weinberger

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

PURPOSE: To describe the indocyanine green angiographic pattern of retinal pigment epithelium tears in the setting of age-related macular degeneration compared with the fluorescein angiographic features.

METHODS: Twelve consecutive patients (12 eyes) with a retinal pigment epithelium tear underwent simultaneous indocyanine green angiography and fluorescein angiography with the confocal scanning laser ophthalmoscope. The findings for the two modes were compared.

RESULTS: Choroidal neovascular membrane was evident beneath the rolled retinal pigment epithelium on indocyanine green angiograms in 11(92%) of 12 eyes: a focal neovascular membrane was apparent in five (42%) of 12 eyes, whereas a plaque neovascular membrane was seen in six (50%) of 12 eyes. In comparison, fluorescein angiography demonstrated late leakage as a result of occult choroidal neovascular membrane in nine (82%) of 11 eyes but no well-defined choroidal neovascular membrane.

CONCLUSIONS: Indocyanine green angiography is superior to fluorescein angiography for imaging choroidal neovascularization in cases of retinal pigment epithelium tear and may serve as an important adjunct to indocyanine green-guided laser treatment in selected cases.

Original languageEnglish
Pages (from-to)331-9
Number of pages9
JournalAmerican Journal of Ophthalmology
Volume128
Issue number3
DOIs
StatePublished - Sep 1999

Keywords

  • Aged
  • Aged, 80 and over
  • Capillary Permeability
  • Choroidal Neovascularization/diagnosis
  • Cohort Studies
  • Female
  • Fluorescein Angiography
  • Humans
  • Indocyanine Green
  • Lasers
  • Macular Degeneration/complications
  • Male
  • Middle Aged
  • Ophthalmoscopes
  • Pigment Epithelium of Eye/pathology
  • Retinal Perforations/diagnosis

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