Single-molecule FRET reveals sugar-induced conformational dynamics in LacY

Keyphrases

• Single-molecule Fluorescence Resonance Energy Transfer (smFRET) 100%
• Conformational Dynamics 100%
• Periplasmic 100%
• Binding Site 40%
• Sugar Binding 40%
• Fluorophore 20%
• Helix 20%
• Distance Distribution 20%
• Single-molecule Fluorescence 20%
• Internal Cavity 20%
• Glucopyranoside 20%
• Six-helix Bundle 20%
• Distance Changes 20%
• Alternating Access Model 20%
• Förster Resonance Energy Transfer 20%
• Symport 20%
• Galactosylated 20%
• Lactose Permease 20%

Biochemistry, Genetics and Molecular Biology

• Dynamics 100%
• Wild Type 100%
• Fluorescence Resonance Energy Transfer 100%
• Binding Site 66%
• C-Terminus 33%
• N-Terminus 33%
• Energy Transfer 33%
• Helix Bundle 33%
• Ape 33%
• Lactose Permease 33%

Immunology and Microbiology

• Dynamics 100%
• Wild Type 100%
• Binding Site 66%
• Energy Transfer 66%
• Face 33%
• Amino Terminal Sequence 33%
• Carboxy Terminal Sequence 33%