Sinonasal-related orbital infections in children: A clinical and therapeutic overview

Sara Torretta, Claudio Guastella, Paola Marchisio, Tal Marom, Samantha Bosis, Tullio Ibba, Lorenzo Drago, Lorenzo Pignataro

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Sinonasal-related orbital infections (SROIs) are typically pediatric diseases that occur in 3–4% of children with acute rhinosinusitis. They are characterised by various clinical manifestations, such as peri-orbital and orbital cellulitis or orbital and sub-periosteal abscesses that may develop anteriorly or posteriorly to the orbital septum. Posterior septal complications are particularly dangerous, as they may lead to visual loss and life-threatening events, such as an intracranial abscess and cavernous sinus thrombosis. Given the possible risk of permanent visual loss due to optic neuritis or orbital nerve ischemia, SROIs are considered ophthalmic emergencies that need to be promptly recognised and treated in an urgent-care setting. The key to obtaining better clinical outcomes in children with SROIs is a multi-disciplinary assessment by pediatricians, otolaryngologists, ophthalmologists, radiologists, and in selected cases, neurosurgeons, neurologists, and infectious disease specialists. The aim of this paper is to provide an overview of the pathogenesis, clinical manifestations, diagnosis, and treatment of pediatric SROIs, and to make some practical recommendations for attending clinicians.

Original languageEnglish
Article number101
JournalJournal of Clinical Medicine
Issue number1
StatePublished - 1 Jan 2019


  • Children
  • Computed tomography
  • Orbital cellulitis
  • Rhinosinusitis

ASJC Scopus subject areas

  • Medicine (all)


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