Small cell undifferentiated carcinoma of the colon associated with hepatocellular carcinoma in an immunodeficient patient

Howard J. Zirkin, Jacov Levy, Leonid Katchko

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations

    Abstract

    Small cell undifferentiated carcinoma (oat cell carcinoma) is a malignant epithelial neoplasm with neuroendocrine features. It can appear as a primary tumor in many organs besides the lung, including the colon. We report a case of primary small cell undifferentiated carcinoma of the left colon with omental metastases in a 23-year-old man with a history of X- linked hyper-IgM syndrome. The patient had a simultaneous primary hepatocellular carcinoma. A literature review of this rare colonic malignancy is presented together with a discussion of the possible relationship of this tumor with hepatic malignancy and immunodeficiency.

    Original languageEnglish
    Pages (from-to)992-996
    Number of pages5
    JournalHuman Pathology
    Volume27
    Issue number9
    DOIs
    StatePublished - 1 Jan 1996

    Keywords

    • X-linked hyper-IgM syndrome
    • hepatocellular carcinoma
    • neuroendocrine tumor
    • oat cell carcinoma
    • small cell undifferentiated carcinoma of colon

    ASJC Scopus subject areas

    • Pathology and Forensic Medicine

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