@inproceedings{4046496a3c33448eb2384472f19de395,
title = "Smith predictor sliding mode closed-loop glucose controller in type 1 diabetes",
abstract = "Type 1 diabetic patients depend on external insulin delivery to keep their blood glucose within near-normal ranges. In this work, two robust closed-loop controllers for blood glucose regulation are developed to prevent the life-threatening hypoglycemia, as well as to avoid extended hyperglycemia. The proposed controllers are designed by using the sliding mode control technique in a Smith predictor structure. To improve meal disturbance rejection, a simple feedforward controller is added to inject meal-time insulin bolus. Simulations scenarios were used to test the controllers, and showed the controllers ability to maintain the glucose levels within the safe limits in the presence of errors in measurements, modeling and meal estimation.",
keywords = "Artificial pancreas, Biomedical control, Sliding mode control, Type 1 diabetes",
author = "Amjad Abu-Rmileh and Winston Garcia-Gabin",
note = "Funding Information: ★ The work was supported by a (BR) research grant to the first author from the University of Girona",
year = "2011",
month = jan,
day = "1",
doi = "10.3182/20110828-6-IT-1002.01213",
language = "English",
isbn = "9783902661937",
series = "IFAC Proceedings Volumes (IFAC-PapersOnline)",
publisher = "IFAC Secretariat",
number = "1 PART 1",
pages = "1733--1738",
booktitle = "Proceedings of the 18th IFAC World Congress",
address = "Austria",
edition = "1 PART 1",
}
