Abstract
FTIR spectroscopy has been widely used in recent time as a efficient tool to biomedical investigations. In this study we examined the potential of FTIR microspectroscopy as analytical instrument for early evaluation of anti-bacterial therapy efficiency. For this purpose, the effect of propolis (PE) on the development of bacterial infection in cell culture was examined. PE is a natural honeybee product with a potent antibacterial activity. Our results show early (2h post treatment) unique and significant spectral indicators for successful treatment with PE. Some of these biomarkers demonstrate different trends in gram (-) compared to gram (+) bacteria. It seems that FTIR spectroscopy can be used as an effective analytical tool for an early evaluation of the efficiency of the antibacterial effect of PE and probably other used drugs.
| Original language | English |
|---|---|
| Pages (from-to) | 43-50 |
| Number of pages | 8 |
| Journal | Studia Universitatis Babes-Bolyai Chemia |
| Issue number | 3 |
| State | Published - 1 Sep 2011 |
Keywords
- Bacteria
- FTIR microscopy
- Propolis
ASJC Scopus subject areas
- General Chemistry