FTIR spectroscopy has been widely used in recent time as a efficient tool to biomedical investigations. In this study we examined the potential of FTIR microspectroscopy as analytical instrument for early evaluation of anti-bacterial therapy efficiency. For this purpose, the effect of propolis (PE) on the development of bacterial infection in cell culture was examined. PE is a natural honeybee product with a potent antibacterial activity. Our results show early (2h post treatment) unique and significant spectral indicators for successful treatment with PE. Some of these biomarkers demonstrate different trends in gram (-) compared to gram (+) bacteria. It seems that FTIR spectroscopy can be used as an effective analytical tool for an early evaluation of the efficiency of the antibacterial effect of PE and probably other used drugs.
|Number of pages||8|
|Journal||Studia Universitatis Babes-Bolyai Chemia|
|State||Published - 1 Sep 2011|
- FTIR microscopy
ASJC Scopus subject areas
- Chemistry (all)